WebSpecial Issue Information. MicroRNAs (miRNAs) are small (19-24 nt) RNA molecules that negatively regulate gene expression. These molecules control many biological … WebFeb 2, 2024 · Biolayer interferometry (BLI) is a widely utilized technique for determining macromolecular interaction dynamics in real time. Using changes in the interference …
Biolayer Interferometry: Protein-RNA Interactions - PubMed
WebDec 10, 2024 · Here, we describe a novel application of biolayer interferometry for the rapid detection of antigen-specific antibody levels in plasma samples, and demonstrate its utility for quantification of ... WebApr 11, 2024 · Small molecule drugs that target viral protease activity have proven to be an effective antiviral strategy (Lu et al., 2024).Discovery Studio 2016 (DS2016)-based molecular docking was performed to screen for small molecular compounds that targeted the active sites of 3CLpros of SECoV that were located in the groove formed between … foxley dentist
Biosensor-based small molecule fragment screening with biolayer ...
WebJun 10, 2011 · Biolayer interferometry (BLI), a technique that measures changes in an interference pattern generated from visible light reflected from an optical layer and a … WebMar 30, 2024 · Biolayer interferometry (BLI) and circular dichroism (CD) spectroscopy were used to investigate the interaction between previously reported i-motif DNA (i-DNA) … WebNov 21, 2014 · Aptamers are segments of single-strand DNA or RNA used in a wide array of applications, including sensors, therapeutics, and cellular process regulators. ... Current assay methodology for characterizing small molecule-aptamer binding is limited by either mass sensitivity, as in biolayer interferometry (BLI) and surface plasmon resonance … foxley coat of arms