Oxysterol-binding protein-related protein 3b

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August undefined, 2024

WebFeb 14, 2024 · Oxysterols accumulate in tissues and exert pharmacologic effects on cellular sterol biosynthesis and uptake. They are oxidized byproducts of cholesterol that cause cytotoxic effects on a variety of cells. Oxysterol-binding proteins such as OSBP1 ( 167040) and OSBP2 may mediate oxysterol cytotoxicity in tissues (summary by Moreira et al., … WebApr 29, 2015 · By whole-exome sequencing in 25 affected members of the family, they identified heterozygosity for a 2-bp deletion (c.153_154delCT; 606731.0001) corresponding to codons 51/52 in exon 3 of the OSBPL2 gene. They also studied 26 unaffected members of the family and found that the mutation segregated completely with the disorder.

Fungal oxysterol-binding protein-related proteins promote …

WebNational Center for Biotechnology Information WebMar 1, 2009 · It binds to oxysterol-binding protein-related protein 3B [62], which is also upregulated in the mutants and is proposed to cycle between the ER and the Golgi [62]. … to pay back for slavery

Oxysterol-binding protein - Wikipedia

Web(Click on the icon in the table below to see search hit context) WebDec 5, 2024 · Abstract. Oxysterol-binding protein-related proteins (ORPs) are a conserved class of lipid transfer proteins that are closely involved in multiple cellular processes in … WebEvidence for rapid, energy-independent transport between organelles has implicated transport proteins, in particular the eukaryotic oxysterol binding protein (OSBP) family. to pay best buy credit card

Entry - *606729 - OXYSTEROL-BINDING PROTEIN 2; OSBP2 - OMIM

(PDF) The mammalian oxysterol-binding protein-related proteins …

WebMar 4, 2005 · Oxysterol-binding protein (OSBP) is the founding member of a family of sterol-binding proteins implicated in vesicle transport, lipid metabolism, and signal transduction. Here, OSBP was found to function as a cholesterol-binding scaffolding protein coordinating the activity of two phosphatases to control the extracellular signal–regulated ... Web32 minutes ago · Among the 42 identified proteins (Fig. 1B–I, Supplementary Fig. 2, Supplementary Tables 1–3, and Supplementary Movie 1), approximately half are conserved in different species (the “core ... to pay by cardWebOxysterol-binding protein (OSBP)-related proteins (ORPs) are lipid-binding proteins that are conserved from yeast to humans. They are implicated in many cellular processes … picmx fund holdings

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Oxysterol-binding protein-related protein 3b

Oxysterol-Binding Protein - an overview ScienceDirect Topics

WebB IBLIOGRAPHY - by the human oxysterol-binding protein (OSBP) Loading... Home Other. B IBLIOGRAPHY ... (BMP), but Not 3,1’-BMP, Increases Membrane Curvature Stress to Enhance α-Tocopherol Transfer Protein Binding to Membranes. Lipids 2015, 50 (3), 323–328. WebThe OSBP-related protein family Protein families displaying sequence homology to the carboxy-terminal sterol-binding domain of oxysterol-binding protein (OSBP; denoted OSBP-related ligand-binding domain [ORD]) are present in practically all eukaryotic organisms [1]. In humans [2,3], as well as in mice [4], the gene

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WebMay 15, 2024 · The oxysterol binding protein (OSBP) is a storied protein in organelle biology. Its early roles include acting as a membrane contact site (MCS) tether as well as a lipid antiporter. A surprising new function for OSBP in MCS dynamics has now been uncovered in a recent study by Jamecna et al. (Dev. Cell 2024;49:220–234). Web3.5 Sterol-transfer protein, Osh4. The oxysterol-binding protein-related proteins (Orp) are conserved from yeast to humans and are implicated in the regulation of sterol homeostasis and in signal transduction pathways. Osh/Orp proteins transport sterols between organelles and are involved in phosphoinositide metabolism.

WebThe present invention discloses agents and methods for inducing osteoblastic cellular differentiation, as well as the use of such agents and methods to treat patients to maintain bone mass, enhance bone formation and/or bone repair. Exemplary agents include oxysterols, alone or in combination with particular oxysterols, or other agents, such as … WebChemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite

WebJan 5, 2024 · ORP3A; OSBP (OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3A; T7H20.150; T7H20_150; UNFERTILIZED EMBRYO SAC 18 Summary Encodes a protein that binds to beta-sitosterol and localizes to the ER. The WFDE motif in ORP3a appears to be important for a direct interaction with PVA12 [Plant VAMP-Associated protein 12]. WebMar 21, 2024 · OSBPL1A (Oxysterol Binding Protein Like 1A) is a Protein Coding gene. Diseases associated with OSBPL1A include Splenic Manifestation Of Leukemia.Among its …

WebMar 14, 2024 · Abstract. Oxysterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) have emerged as potentially druggable targets in antiviral and precision cancer …

WebMay 17, 2024 · Oxysterol-binding protein-like 2 (OSBPL2), also known as oxysterol-binding protein-related protein (ORP) 2, is a member of lipid transfer protein well-known for its … to pay best buy credit card onlineWebID: OSBL1_MOUSE DESCRIPTION: RecName: Full=Oxysterol-binding protein-related protein 1; Short=ORP-1; Short=OSBP-related protein 1; FUNCTION: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional … to pay cashWebApr 6, 2024 · The blue fluorescent protein (BFP) was cloned from the pLVX-BFP plasmid. The PH domain of oxysterol-binding protein (OSBP) and human heat shock protein family A member 5 (HSPA5) gene were cloned from the THP-1-cell cDNA library. ... (Figure 3b). HSPA5 is a member of the heat shock protein 70 (HSP70) family and localizes to the ER … to pay bmw for a card