Web1 Mar 2024 · Of fosphenytoin reloading doses that were administered, 48% (73/152) of doses resulted in a therapeutic free phenytoin concentration on the subsequent day, with the remaining 52% resulting in nontherapeutic levels (39% subtherapeutic, 13% supratherapeutic) (Table 3). Total levels were rarely collected (9/152) and were not … WebIn an attempt to determine whether the dose of an antiepileptic drug should be increased in epileptic patients who were seizure-free and had subtherapeutic serum levels, 79 patients …
Phenytoin Information for Prescribing, Monitoring and …
WebConversely, phenytoin levels may increase with coadministration of eslicarbazepine, and adjustment of phenytoin dose may … Convulsive status epilepticus in adults: … WebThe therapeutic range for phenytoin - A reappraisal Authors M Feeley 1 , B Duggan 1 , M O'Callagan 1 , N Callaghan 1 , J Seldrup 2 Affiliations 1 The Departments of Neurology and Biochemistry, Cork Regional Hospital, Wilton, Cork. 2 Mathematical Analysis Section, Ciba Geigy, Macclesfield, Cheshire. PMID: 27517387 DOI: 10.1007/BF02938049 facts on bubble gum
NHS Tayside Phenytoin Prescribing and Monitoring …
Web4 Jan 2014 · This could be explained by changes in the volume of distribution or in the intrinsic clearance of phenytoin. The difference in phenytoin concentration between pre- and postdialysis is of concern, as 70 % of patients had subtherapeutic levels for the unbound drug (<4 μmol/L) after hemodialysis. Web100mg phenytoin sodium (capsules/injection) = 90 mg phenytoin base 9,10 (suspension) Suspension (90mg/5mL) is available for NG administration or those with swallowing problems. Dose conversion is however required and interaction with other medications … Web15 Jan 2024 · Phenytoin has a narrow therapeutic window, between 10-20 mg/L. Serum concentrations of phenytoin are monitored by measuring the total phenytoin … facts on booker t washington