WebSep 2, 2016 · Thiolated sodium alginate (TSA; 2 or 4%) constituted the outer drug free layers to enhance mucoadhesion and achieve controlled drug release. Optimized formulation … WebNov 1, 2010 · The thiolated alginate species synthesized had bound thiol content ranging from 247.8±11.03-324.54±10.107 ΅mol/g of polymer depending on the reaction conditions.
(PDF) THIOLATED MORINGA EXUDATE GUM AS IMPROVED BIO …
WebMay 27, 2015 · Alginate modification via click chemistry for biomedical applications. Carbohydrate Polymers 2024, 126 , 118360. ... In situ thiolated alginate hydrogel: Instant formation and its application in hemostasis. Journal of … WebFeb 10, 2024 · Thiolated alginate. Alginate is an anionic polymer derived from brown algae made up of β-D-mannuronic acid and α-L-gluronic acid residues linked by 1,4-glycosidic linkages. It has widely investigated for several biomedical applications like drug delivery, … chinwe meaning
1 H-NMR spectra of (A) sodium alginate and (B) MPA.
WebSep 2, 2016 · Thiolated sodium alginate (TSA; 2 or 4%) constituted the outer drug free layers to enhance mucoadhesion and achieve controlled drug release. Optimized formulation was assessed clinically on 20 subjects. Results: Films were uniform, thin and hard enough for easy insertion into periodontal pockets. WebThiolated alginate was developed into blank disulfide cross-linked nanoparticles by referring to 10 with few alterations. Briefly, 10 mg thiolated alginate was dissolved in 0.25 N sodium hydroxide solution (10 mL) and stirred in an ice bath for 1 h at 1000 rpm. Afterwards, the solution was left to react in the dark at 25 °C for 24 h. WebAug 11, 2016 · An in situ formed hydrogel was synthesized by sodium alginate and cysteine methyl ester, which turned the sodium alginate into thiolated alginate (SA-SH). SA-SH can … grant ave and bush street